They're obviously not related by immigration group either. The Hopi descend from early first nations. The Navajo descend from the athabascan migrations. Yukon comes from Canadian and British gold rush populations. Alberta comes from various prairie settler efforts, including Ukrainian Canadians. The Mormons were their own settlement group in Mexico that went to war with many of the (now-) surrounding indigenous nations. Etc.
And this is just one "American nation". The same basic issue exists in all of them.