I recently posted about our first stab at this at https://vishakh.blog/2025/07/08/using-mpc-for-anonymous-and-....
We'll have a waitlist up pretty soon for people to sign up for a batch of private sequencing.
In the first case (reducing risk factors), chances that you will at least check positive for one thing are almost 1 (certain) and you don't need a test to know that. In almost all cases, limiting the risk will involve a) eating well b) stopping alcohol / smoking c) regular physical activity d) taking some Aspirin for the remainder of your life. You don't need the test results to start doing this. Either you sincerely want to live longer and shouldn't wait for genetic screening to take your matters into your own hands, or you think that test results will suddenly turn you into a monk. News flash: won't happen.
In the second case (whether or not to procreate): any decision you make on the hypothesis that your children will inherit it and that science will not have solved it in the next 50 years will very likely be a bad reason to not have children (there are many good reasons to not have children, though, but having a rare genetic conditions is not a good reason).
The only people who should not have kids are bad parents and people who don't want kids. Guess what? These two groups that probably have the highest amount of kids on Earth.
If the report showed you had a chance of developing say Parkinsons, how would that change your life now? Could you implement those changes regardless?
I mean, pretty much all genetic markers are just "risk". And lifestyle choices (smoking, drinking, sugar, exercise et al) seem to be well known, and "good for everything". So, knowing that, it seems like there's lots you can do regardless of genetics.
I confess, for me personally, I'm not really interested in my genetic risk factors. Much less my Neanderthal content. Hence the genuine question- what will it tell you thst you care about?
Even then, you'll need expertise in analysing the output reads. And EVEN then it's difficult to accurately assess variants.
Using DIY tools and not being a trained biostatistician or whoever usually looks at these things you are very likely to face errors you don't know how to account for. I would guess the odds are high you'll encounter scary false positives for example.
It sounds really fun though, something I've always wanted to do with more time.
All doctors (including concierge) use 3rd party services for practically everything from blood work to imaging to application products. It’s safe to say that it’s very likely that they’ll outsource the genetic testing to a 3rd party
