This [1] is from his final stream, and it's clear he was already at the breaking point. I feel most awful for his friend Bortnyk (one of the two voices you hear in the background there essentially having an intervention), he's going to be beating himself up thinking he could have done more, for years to come.
Everybody could see Danya deteriorating, but somehow I think nobody really realized just how 'real' it was. Magnus, who also regularly followed Danya's streams, has mentioned that he somewhat regrets not coming out publicly in defense of him. Probably in part because his views on cheating were already somewhat tainted at this point, and probably in part because nobody wanted to be the next person Kramnik started going after.
And another point in the video where it gets quite dark: https://youtu.be/112JImX_cWM?t=2615
Such an awful thing to see such an amazing person melt away and ultimately leave this world. Literally about a week ago I was recommending him on here to people trying to learn chess. His ability to teach was unparalleled.