Recently, I did a major python refactoring project, converting a prototype/hack/experiment into a production-quality system. The prototype heavily intermixed IO and app logic, and I needed to write unit tests for the production system. Even with fixtures and mocking, unit testing was painful and laborious, so our test coverage was lousy.
Partitioning the core classes into pure and impure components was the big win. Unit testing became trivial and we caught lots of bugs in the original business logic. More recently, we changed the IO from files to a DB and having encapsulated the IO was also a win.
