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0 pointszahlman4mo ago0 comments

> An excess of vitamin D causes abnormally high blood concentrations of calcium, which can cause overcalcification of soft tissues, including arteries and kidneys. Symptoms appear several months after excessive doses of vitamin D are administered. A mutation of the CYP24A1 gene can lead to a reduction in the degradation of vitamin D and thus to vitamin toxicity without high oral intake (see Vitamin D § Excess).

> Treatment

> In almost every case, ceasing vitamin D intake, combined with a low-calcium diet and corticosteroid drugs, will allow for a full recovery within a month. Bisphosphonate drugs (which inhibit bone resorption) can also be administered.[2]

Regardless, blood levels need to be checked for this sort of thing and doses are not one-size-fits-all. I also once was taking 10k daily, for several months, and ended up just barely in excess territory with no noticeable symptoms. (I settled on taking 4k daily in the long term.)

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cj4mo ago

> In almost every case, ceasing vitamin D intake, combined with a low-calcium diet and corticosteroid drugs, will allow for a full recovery within a month.

Surprised to see just 4 weeks for a recovery. I got retested after 8 weeks (only minor improvement) and wasn't until 16 weeks until the test finally came back in range.

100% no dose is one-size-fits-all. I overdosed from taking a specialty multivitamin (it has a discord channel and everything). So was chatting with people taking the same vitamin, same dosages, also getting tested, but others had no issues at the same doses.

I guess I just absorb vitamin D with great efficiency, who knows.

johnisgood4mo ago

> An excess of vitamin D causes abnormally high blood concentrations of calcium

That is what supplementing K2 with D3 is for, too.

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