Much more so than before, I'll comfortably reject a PR that is hard to follow, for any reason, including size. IMHO, the biggest change that LLMs have brought to the table is that clean code and refactoring are no longer expensive, and should no longer be bargained for, neglected or given the lip service that they have received throughout most of my career. Test suites and documentation, too.
(Given the nature of working with LLMs, I also suspect that clean, idiomatic code is more important than ever, since LLMs have presumably been trained on that, but this is just a personal superstition, that is probably increasingly false, but also feels harmless)
The only time I think it is appropriate to land a large amount of code at once is if it is a single act of entirely brain dead refactoring, doing nothing new, such as renaming a single variable across an entire codebase, or moving/breaking/consolidating a single module or file. And there better be tests. Otherwise, get an LLM to break things up and make things easier for me to understand, for crying out loud: there are precious few reasons left not to make reviewing PRs as easy as possible.
So, I posit that the emotional reaction from certain audiences is still the largest, most exhausting difference.