We can already change the maximum lifespan of some other species. Why shouldn’t we expect to gradually be able to do it for more species? And then what makes humans special that we couldn’t eventually do the same for humans?
And my point was-no matter how hard human life extension is, mind uploading is many orders of magnitude harder. The first, it seems likely in principle that we could achieve it if only we knew the right genetic changes to make-now, you may be right that in a thousand years we still won’t work out in practice exactly what they are-but human life extension has a certain kind of theoretical in principle feasibility which could well coexist with practical infeasibility; mind uploading lacks even that level of theoretical in principle feasibility.