I worked on a large commercial AlpineJS app and grew to really, really hate it. It's great for smallish projects where the limits of the tool are known, but it is in no way a drop-in replacement for something like React (and I am no fan of React). People like to throw around how easy it is to do basic things, but building a real app using Alpine is an absolute nightmare.

Alpine data objects can grow to be quite large, so you wind up inlining hundreds of lines of JS as strings within your HTML template, which often limits your editor's ability to do JS checks without additional config.

State management in Alpine is implicit and nested and not a serious solution for building commercial apps IMO.

And don't even get me started on unsafe-eval.

If it's your hobby app and you are the developer and the product owner, go for Alpine. If you're working at a company that is asking you to build a competitive web product in 2025, use a more robust tool. Hotwire and Stimulus has scaled much better from an organization standpoint in my experience.