The idea of "skins" is apparently to push that even further by abstracting the concrete syntax.
This has limits.
Files produced with tab=2 and others with tab=8, might have quite different result regarding nesting.
(pain is still on the menu)
More than that, in the general case for common C like languages things should almost never be nested more than a few levels deep. That's usually a sign of poorly designed and difficult to maintain code.
Lisps are a notable exception here, but due to limitations (arguably poor design) with how the most common editors handle lines that contain a mix of tabs and spaces you're pretty much forced to use only spaces when writing in that family of languages. If anything that language family serves as case in point - code written with an indentation width that isn't to one's preference becomes much more tedious to adapt due to alternating levels of alignment and indentation all being encoded as spaces (ie loss of information which automated tools could otherwise use).