The protests are, by credible reporting, huge, reflected in the scale of the number of arrests and fatalities. Their antecedents include sky-high unemployment, the highest inflation rates in the world, and water and power rationing --- far more severe and far more directly material conditions than what preceded the 2022 protests. Diverse outlets have the signal chant of the protesters "Neither Gaza Nor Lebanon, My Life Only For Iran", which correlates well with the belief the the IRGC is effectively an Iranian version of the KGB, a second "inner society" whose large membership has preferential access to everything ordinary Iranians don't.
Some of this is disputable, much of it isn't. Meanwhile:
* There's no evidence that foreign powers are behind these protests, just narratives. The track record on unsupported but convincing-sounding narratives everywhere is pretty bad; nowhere is it worse than in this part of the world.
* There's no evidence that the protests themselves are pro-US (and certainly not pro-Israel; most of the protesters probably don't like Israel!). They just want water, jobs, and currency that can reliably buy food.
* There's also not much evidence that any major government in the world wants Iran toppled. Iran is incredibly weak right now. Regional powers like Turkey, Saudi, and especially Israel --- which has basically depantsed the IRGC --- don't actually have much to gain from an Iranian overthrow, but the whole region has a lot to lose from instability.
So yeah, I'd say: pretty extraordinary claim --- again, that claim being, "the anti-regime movement is the product of foreign intervention".
I want to keep saying: I don't think the protests will be successful. It's a state specifically designed to prevent protests movements like these from being successful! They may suck at air defense, but I don't think they're bad at putting down rebellions.