I think the way a drug impacts the brain is kind of important
Growth of single human organs or organ tissue is easier, cheaper and less fraught with political peril.
Unfortunately, they can vote.
There are multiple examples in the literature of people leading perfectly ordinary lives whilst unknowingly having no more than 5% of the typical amount of brain matter (typically because of hydrocephalus). For example, https://www.science.org/doi/10.1126/science.7434023 from 1980.
The brain is indeed incredibly resilient - some kids with serious epilepsy get an entire hemisphere taken out - but which 5% you're left with matters enormously.