A day, having 86_400 seconds in it, is equivalent to 4_320_000 pulses at 50 Hz. At 49.975 Hz, it's only 4_317_840 pulses which is 2_160 pulses too few. Which, at assumption of 50 Hz, translates into discrepancy of 43.2 seconds, in this one day.
So, no, it's a pretty big discrepancy actually, over here anything over 0.2 Hz is legally declared to be "degraded quality", and it's been debated for years that this is actually a way too wide margin but the electricity providers/grid operators managed to successfully argue that they can't afford upgrades.
Moral of the story: don't get cute when designing electronics, just use AC/DC power supply and put a damn crystal oscillator as every other reasonable person.