What are you worried about? If it's support or API, don't be. There is a ton of support for Node.js already. As far as web technologies go, I dare say Node.js has approached stability by now. Personally I love the asynchronous flow which is comparatively simple to implement and it only took me a day to go from zero to building a webapp in Node.js. However, you'll be working in JS. For small things it's bearable. For larger projects it's a pain, at least for me.
As a related question, has anyone tried using Node.js as the final glue code, taking advantage of easy asynchronous function implementation while writing the core logic in some other language? I know you can technically do that but I don't know what overhead I should expect if I attempted it?!
