Do not use global admin or admin account as daily driver for one. Dont save it in browser etc either.
Limit roles, even within the application, here Intune.
Office 365 also has conditional access and many policy leavers to tweak, many cases of people locking themselves OUT of 365. So the gates work but you need to configure them.
"Break glass" global admin accounts now also require MFA. https://learn.microsoft.com/en-us/entra/identity/authenticat...