All frameworks make some assumptions and therefore have some constraints. There was always a well-understood trade-off when using frameworks of speeding up early development but slowing down later development as the system encountered the constraints.
LLMs remove the time problem (to an extent) and have more problems around understanding the constraints imposed by the framework. The trade-off is less worth it now.
I have stopped using frameworks completely when writing systems with an LLM. I always tell it to use the base language with as few dependencies as possible.
