You should run away from React Native Desktop screaming. It's built on top of WinUI 3, and inherits all it's problems, while also being dramatically slower. Almost all functionality requires writing C++ code, and communicating between C++ and JS is a huge pain in the ass. Use QT instead.
And if you think using it will let you port your app to other platforms, think again. There's no drop-in compatible equivalent of RNW for Linux, and the version for Mac is even worse than the Windows version.
t. works on a huge app written with React Native Desktop