It's always worked for me manually (straight domain replace, rest of the URL untouched), so I believe so. I'd certainly find it handy if it were offered automatically in the top text. :)

xcancel.com seems to work at least as well as any other still-maintained nitter instance. Here's a list:

https://github.com/zedeus/nitter/wiki/Instances

Thanx. I tried to use several of these services (because I don't use Twitter/X myself so got context from a Dutch website) but didn't get it to work (was very probably just me). Xcancel is indeed a much better experience.