I doubt a MW laser can reliably intercept a reentry vehicle. A lot of energy is lost through the atmosphere when intercepting a warhead in space, from a land based laser. Once it reenters the atmosphere there might not be enough time. You also need to burn through the heatshield that the warhead is equipped with for reentry.

Even if you can can deliver enough energy for long enough, there is no fuel to burn and it might not be easy to detonate or disable the warhead.

For ICBMs, one idea was to use orbital, nuclear powered lasers to hit the missile on the boost phase.

But that's very much not near-future.

Lasers might still be useful for rockets, drones and cruise missiles of course.

Maybe for subsonic, high end missiles I'm extremely skeptical. Need 5-10MW to get useful dwell power on high end hypersonic inherently shielded against reentry thermals. Speculative laser defense are infra size defense, not mobile trailer size. Factor in duty cycles (i.e. shots per minute) and it seems dead end. Half of economics of missile defense is mobility - building density relative to threats by moving platforms. Last 2 parts real constraints, high-end adversaries coordinate salvos to arrive in time. Interceptor magazine depth limited = still throw 100s of interceptors to engage multiple targets if required. Lasers = serial visual range engagement. Figure out dwell time + duty cycle to saturate. Hypersonic can go from over horizonal to hit target in 10 seconds, a laser couldn't engage more than 1-2 missiles in that time. Technically 1, because by the time you fried 1st target the 2nd is so close the shrapnel will hit on momentum.

Lasers are not "all weather" weapons as far as I am aware. Clouds, snow, fog, rain, and just humidity all degrade their performance greatly.

Try that on my spinning, mirror-coated missile!