An F-35 is of course going to absolutely outclass any drone. But a hundred million (roughly) spent on drones is going to do more damage than that F-35 and is going to be more versatile.
The second that F-35 lands it is going to be at risk from a (low cost) drone attack. And some aicraft aren't even safe in the sky anymore:
https://www.youtube.com/watch?v=ACjCP-Dt3GY
Speaking of Aircraft Carriers, how is the Ford doing?