I understand that everyone has their own needs and Linux still might not be a great fit, but just in case it's helpful, here are some possibly-comparable Linux-friendly alternatives to what you mentioned:

> Fusion360

Depending on your needs, Onshape could be a good portable option since it runs in a browser. I use it for all my 3D printing pursuits and have made some fairly complex parts. And it's free if you don't mind people theoretically being able to search for and see your work. Not a problem for me since I'm not doing anything proprietary or making BDSM gear or whatever---if my shitty projects help somebody else with theirs, I'm all for it.

> OneNote

I don't think Obsidian does synchronous collaboration well (could be wrong) but for asynchronous collaboration it ought to be fine; their sync product works very well and I haven't ever had to fiddle with anything. My non-technical wife could use it with no issue (but in practice we use Apple Notes).

I don't think it's a drop-in replacement for OneNote, but it might serve the purpose.

> zero tolerance for needing to tweak settings to make a game work on Linux

This has gotten a lot better. With a distro like Bazzite (which I just use as my general purpose desktop now), pretty much everything works out of the box unless it has an anticheat that's specifically blocking Linux.

I would not have been willing to say this a year ago (and I know plenty of people have been saying it for a long time, and I generally disagreed with them), but today I really think gaming on Linux is ready for general adoption. In the last few months I've totally abandoned Windows for gaming, which was the last thing I was using it for (in a VM).