A mac with 256 GB memory would run it but be very slow, and so would be a 256GB ram + cheapo GPU desktop, unless you leave it running overnight.
The big model? Forget it, not this decade. You can theoretically load from SSD but waiting for the reply will be a religious experience.
Realistically the biggest models you can run on local-as-in-worth-buying-as-a-person hardware are between 120B and 200B, depending on how far you’re willing to go on quantization. Even this is fairly expensive, and that’s before RAM went to the moon.
