I never left anything valuable or personal at my desk when I worked in an office simply because I had a very nonzero number of colleagues who acted like animals. My fizzy waters, coffee, and snacks would be consumed without permission or replenishment. Chairs, monitors, and input peripherals would get swapped without asking. Desks surfaces would be sat on with chairs used as footstools. Corporate effluvia of all types would end up on my "unused desk" because I wasn't in at the exact moment some roving bandit walked by looking for a spot to dump their crates of paper and binders.
Some people simply have no regard for others and will mess with or jack your shit. Don't give them the chance.