This is unknowable.
That fits the definition of a simulation.
I don't agree with this argument, but it circulates occasionally.
If you are in a sim, then the sim execution is an expensive process, it produces heat and consumes energy. If you are in reality, a material body, then keeping alive also consumes energy. The debates about consciousness often assume a cost-free regime, a platonic perspective. I think this is wrong. We have much to gain thinking about how a process provides its own energy, or how it balances costs and gains. Maybe we can find answers about consciousness too if we chase down the cost recursion path.
If simulation theory (or similar ideas) are real, it's entirely possible that the "real world" running the simulation operates on completely different physical laws than the simulation.
You can never really disprove that some malicious entity is just making you think you're seeing the stars and talking to people, if you want to go back to philosophy about it. There's a bit of assumed faith