Around the same time, decades ago (and until recently), my father (a post-tension concrete expert, P.E.), was still using an early 1980s DOS program to design 8- & 9-figure government facilities.

I guess the span deflection/moment/&c calculations don't really change much (i.e. get fancy) on brutalist state buildings. But he did grow up hand-drafting blueprints (I remember the ink/smell from my childhood) and did have a regular 3D/CAD technologist for fancier designs (he despised architects' more-esoteric "Vision").

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Wouldn't much of modern chemistry rapidly be integrating/upgrading within python environments (e.g. AlphaFold) on much-faster equipment? I know a few PhDs that are blown away by recent advances in dissertation-level output from machines — in days vs. entire graduate programs – and even walked the graduation stage with (now-Nobel Laureate) John, an Alphafold co-publisher... obviously his perspective is unique/polar.