I posit: everyone is depressed, all the time. Start-ups are not unusual.

In the US, 9% of people report being depressed at least occasionally, and 3.4% are majorly depressed. An estimated 26% suffer from a diagnosable mental disorder in a calendar year (shout out to anxiety disorders!).

http://www.nimh.nih.gov/health/publications/the-numbers-coun...