In a single meeting, I believe it is often easy to determine if there is likely to be no fit. Going with your gut here makes a lot of sense.

But it is completely unrealistic to believe that in a single meeting you will be able to predict with any certainty that a candidate will work well with your team, enjoy the position and remain loyal. You simply can't establish these things until a person is on the job.

If you do a good job not hiring obvious poor fits, the odds that your relationship with your new employee will be a fruitful one obviously increase, but don't fool yourself into believing that there isn't a lot of luck involved.