I think the dot com will be the traditional bet, but over time become one of those 'nice-to-haves' - - with the ridiculous amount of squatting on the most bizarre terms, other tlds are becoming far more attractive.
Above this, the dot co people are making great strides in offering a wide range of benefits to signing on. Not only discounts and freebies, but the potential of a community. In the future, I think more tlds will adopt this model to attract business.