I agree and have no qualms with people's use of heroin, and have dabbled, myself. It was only presented as an example.
To amplify, there is nothing morally wrong with anti-depressants either. However morality is not the issue of my concern, the deadening of true self is.
Most descriptions of depression I have read sound like "the deadening of the true self" is what depression does, and any effective treatment would rather be the revival of the true self.
I think you misunderstand what I mean by true self. Yes, our self does change at every moment and is "reborn." However, it is still a true self as it is not artificially modified.
I find it extremely doubtful that you can actually give a definition of "true self" which meets the following conditions: 1) coherent and non-contradictory, 2) in accordance with reality, and 3) something a person should care about preserving.
I find it even more doubtful that you can give a definition of "artificially modified" which is meaningfully distinct from natural change.