deadbeef is a very nice lesser-known linux music player that's heavily influenced by foobar2000. quodlibet is probably my second favourite, but it's written in python, so it can be a bit slow/heavy on resources at times. banshee is great for large libraries and as an iTunes replacement.
I switched to quodlibet for the fast indexing and searching of large libraries. I'm sure other media library managers do that too, but it seems to be very nice in quod.