The most severe problems were the result of a new doctor in their residency changing my long-acting insulin to an intermediate that was also a 30% mix of fast acting, in an attempt to drive my A1C to under 6. This created a serious problem of wanting to give myself insulin for a meal, my blood sugar only being around 90-100 mg/dL, and then being unable to decouple the fast-acting from the intermediate since it was pre-mixed. I hemmed and hawed, but the attending stood by the decision to change to 70/30. I had to change 10 years of regimen instantly, which was fraught with peril.
Two serious episodes later, and a waiting room at a prestigious teaching hospital hearing someone scream, "Your stupid decision has nearly killed me twice", and I'm now back on the long-acting with insulin reactions being rather infrequent (twice a month), and nowhere as severe (catching it around 65-70 mg/dL). My A1C has trended up slightly (6.1-6.2 to 6.3-6.4), but I'd rather that than death by overdose.
The first thing my endocrinologist asks when I see him (literally, before he even asks how I'm doing today) is if I can still feel lows. I think he'd get me on a CGM pretty quick if I reported I couldn't.
I'm super interested in this contact lense solution.