You can change things, but sometimes it's better to walk around the brick wall or climb over it, instead of having a conversation with the wall asking it to please move out of the way for you.
[Edit: Can't reply to message below so I'll clarify here - my intent was that instead of arguing with politicians, they could consider options that wouldn't even involve politicians. Coursera could close their US business and move to a country that does not have the same restrictions. Doing so may also help persuade US politicians that their policies are having the reverse impact of what they want.]
