I feel like the "immaturity" argument is just an excuse. Bitcoin itself is young, but we know how to handle encryption materials safely, we know how to process online transactions, we know how to write exchanges, etc. Mt. Gox wasn't taking on any new problems here. Most of the new stuff that goes into Bitcoin is abstracted away by the Bitcoin protocol.
It'd be very nice for newer players with extensive experience in this area to step up. If not with a new service, then maybe fortifying an existing one (like Coinbase).