Probably quite a few, especially those like Drew Houston who didn't get in on their first try. Presumably on that first application Drew had some of the same good credentials (MIT grad, perfect SAT score).
It's a shame YC doesn't provide feedback on applications…I'm sure they make notes as they go through the apps (at least for the ones they're not sure about) — would be great for them to have a system to include those notes with their decision notifications!