I'd really love to see a micro-kernel with just enough drivers to run on modern hardware, then tied to a higher level platform. I know it may seem really weird, but would love to see node running on something like this. I know there's been some work on getting something like node working with embedded systems via translation, or communication channels, it'd just be nice to see this micro application to something larger, and removing the extra overhead in said system.
Again, just a weird, warped thought here... Hell even getting golang or or rust would be cool. Something you can run some code on without a lot of baggage that you aren't using. I love where coreos is heading, and would love to see something even lighter.