But if you're hunt a peck QWERTY typist who decides to pick up touch typing, choosing an ergonomic layout like Dvorak or Colemak makes sense. You're essentially staring from zero anyways so you're not wasting much time on the layout anymore so than you would on the QWERTY layout.
This way, you retain your two-finger QWERTY skills while learning a layout that minimizes the odds of developing RSI.