Every question you ask is going to be manifest in relationships between subsets of observable states of reality. Even if you ask a nonsensical question, it is possible to determine
that the question is nonsense by observing the context of the question. There is nothing here that prevents science from working to answer the question.
If you have a question with no possible scientific answer, then it has no answer at all. You do not get better results by refusing to use the best tools.