I am actually speaking from personal experience as an ex-founder with a disability. My disability didn't stop me from founding a company (nor did it stop me from becoming a state championship athlete and being one of the first from my hometown to ever become admitted into a top-10 university), but an unrelated chronic health problem kept me from being as productive as I needed to in order to succeed in business.
A lot of health conditions can be worsened by overwork (remember Sam Altman got scurvy while building Loopt?), and founding a startup is one of the hardest things you could possibly do. I know plenty of otherwise healthy people who ended up damaging themselves while trying to start companies.
To this day, I'm still recovering. Overworking and putting yourself in overly-stressful situations is UNHEALTHY, full stop. I made necessary trade-offs (as any sensible founder would) by eating cheaper food, skipping doctors' visits, cutting back on sleep, falling behind on exercising, and getting bargain basement health insurance. In retrospect, I definitely regret it.
It's a bit offensive to me that you are on here virtue signaling as some champion of anti-able-ism even though you are likely perfectly able yourself.