Personally, I think this interpretation of polygenic risk scoring is a crock of irreproducible shite. I don’t think it’s your fault, I think a lot of people in the field are shilling something they don’t have for grant money, and they’ve created an exciting sci-fi yarn that’s easy for people outside the field to digest.
Height is a univariate trait that does not change after the age of ~20. If you show me someone who can take a genome and predict adult height within a centimeter, then I’ll believe they have a snowball’s chance of predicting something as nuanced and varied as “attractiveness” or “intelligence”.
I think there’s promise in applying PRS to assessing risk for non-Mendelian disease, but there’s far too many social and environmental variables at play to reliably predict these softer features. Like other people have joked, if you want a single number that best predicts educational attainment, use a zip code.
