DuPont, Pfizer, Ford and GE are in industries that are not plagued by patent trolls. That they're against it tells you nothing about how it would affect them because they don't experience the problem the legislation solves, so it necessarily creates nothing but downside risk for them. No matter how small that risk is, requiring them to put their full support behind it in order to fix somebody else's problem is requiring reform to fail.
But it is also disingenuous to suggest that they are the major force against reform, because the bill is quite well targeted specifically at patent trolls. The downside risk for Pfizer et al is extremely small. They may not support it but it's hardly going to put them out of business if it passes. What it would do is put a huge number of patent trolls out of business (along with the lawyers that represent them), and in so doing save a huge number of jobs at the startups they would have extorted or bankrupted. Which is why everyone is saying that the trial lawyers are the ones that most wanted to kill reform -- because the trial lawyers are the ones that most wanted to kill reform.