netrix

I would like to develop an application (not necessary a web page) that will be able to handle my requirements which are:

* file uploads (with meta-data) which I would like to store in one specified directory on server (meta-data would be in SQL database),

* text data (with structure or without),

* handle JSON queries so I will be able to get information/data from server.

Is there any kind of framework that will allow me to quickly create such application and help me storing and retrieving data with JSON queries?

Maybe (but not necessarily) there is a python framework for that?